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Loss of a small region in band 5p15.2 (cri du chat critical region) correlates with all the clinical features of the syndrome with the exception of the catlike cry, which maps to band 5p15.3 (catlike critical region).
The results suggest that 2 noncontiguous critical regions contain genes involved in this condition's cause.
Fewer than 10% of cases have other rare cytogenetic aberrations (e.g., interstitial deletions, mosaicisms, rings and de novo translocations).
The deleted chromosome 5 is paternal in origin in about 80% of de novo cases.
Once the child has survived the first few years of life, the prognosis is good and the morbidity level is low.
Children may be treated by speech, physical and occupational therapists.
If infants have difficulty in suction or swallowing, then physical therapy should begin in the first few weeks of life.
For five days in early October, Dutch artist Dries Verhoeven broadcast his Grindr chats onto a projection screen inside a glass cube situated on a public square in Berlin's Kreuzberg neighborhood.
The project, called "Wanna Play," used Verhoeven's Grindr profile to draw chat partners into a discussion about online intimacy.