Usp 797 medium risk beyond use dating
Despite the 9-year tenure of USP some of these practices persist as a result of their past success, convenience, and the comfort level of health care personnel.As owners of the medication use process, pharmacists should continue to work with their colleagues in other professions involved in the preparation and administration of sterile products to ensure that immediate-use practices are not only compliant with the national standard, but also that they are accurate, cost-effective, and safe for the specific patient population in question.
The authors concluded that contamination risk still exists in both environments, but appears to be higher in ward environments and when doses are prepared individually rather than as part of a batch procedure. Given this established risk of contamination, as well as the absence of quality assurance measures to address compatibility and stability, it is imperative that pharmacy departments describe and utilize practices to minimize immediate-use compounding when possible.
The publication of the USP in 2004 represents the first official enforceable standard for sterile compounding in the United States.
Prior to its publication, there was little monetary or official support for pharmacies looking to improve their compounding processes, despite thousands of cases of septicemia from exposure to compounded intravenous (IV) from the 1970s on.
Despite the lack of direct oversight of areas that carry out immediate use compounding, pharmacy departments can increase their contribution to ensure that best practices are met by addressing a variety of requirements.
In 2007, the Centers for Disease Control and Prevention published a guideline for preventing transmission of infectious agents in the health care setting.